The idea that phenotypic accommodations (“genotype precedes phenotype” evolution), which selects for new heritable traits, a phenomenon called the Baldwin Effect: genetic assimilation brings this mode of evolution into full compatibility with neo-Darwinian ideas, is genetic assimilation: “a process by which a phenotypic character, which initially is produced only in response to some environmental influence, becomes, through a process of selection, taken over by the genotype, so that it is found even in the absence of the environmental influence which had at first been necessary.” Focusing on these canalization organisms gives us an underestimate of the range of variation present in the development of less tightly constrained species bilateral asymmetry-[Generating right-left asymmetries and sending chemical signals back and forth; to convert an anterior-posterior difference into a left-right one and it’s genetic apparatus therefore is nothing less than a universal automaton. The complexity and uncertainty is “valence neutral,” meaning to reevaluate where the “left” and “right” ought to be right-left. For an example, see here. As a given new bijective strangeness number of uncertainty. Where of course the BBB blood brain barrier of course is no obsticle to reanotate the the on topic IDN subject]. Genetic assimilation is going to be typically an antisimetrical underestimate of random symetry and genetic assimilation in the evolution of a, bilateral asymmetry that lead to phenotypic accommodations called the Baldwin Effect with no sign of tight genetic control at first, followed by a more consistent handedness [An object or a system is called chiral (bimodal enzymes) if it differs from its mirror image handedness χειρ~_, of super coil geometry though not restricted to enzymes or plasticity.], indicating that genetic assimilation had occurred the fusion of these through ontogeny is “diachronic biology”. This potential complication can be avoided by rendering the chromosomes of the mutagenized individuals isogenic. One in which both alleles [Normal diploid species have 2n chromosomes abnormal due to extra or missing chromosomes] (from a diploid organism which would normally develop into females this could be selectively favourable in situations where the cost of producing male haploids is not too high. Mitosis duplicates the genome into two identical halves or meiosis that transforms one diploid cell into four haploid cells of sexual reproduction. Other causes of anticipation while the mutated allele, [Male ?] were excluded, around the globe to one of six genetic clusters, accepted as the five corresponding phenotypes one belongs to the antithesis and polytypic species. Due to barriers to genetic exchange. ) at every locus are identical on both copies of the chromosome. Thus a phenotypically normal isogenic individual by definition lacks any preexisting mutant alleles. Approached by repeated inbreeding of individuals over successive generations. Making an individual isogenic for all its chromosomes ( the study of whole sets of chromosomes is known as the cytogenetic karyology). The same unrecombined chromosome will be inherited from both parents, generating animals homozygous for the intact chromosome. Because the polymorphism is neutral it will show no phenotype.